“MIRENA is inserted into the uterine cavity. It has been shown to be effective for up to 8 years for contraception, and up to 5 years for the indications of idiopathic menorrhagia, and protection from endometrial hyperplasia during estrogen replacement therapy”
Bayer’s Australian product information is catching up with the rest of the world from the 5th of June 2024. Unfortunately, it is still easy to find outdated PI still on the web and be misguided.
Did I hear this important news from Bayer? No, it was through a GP Facebook page called GPDU, yah social media.
The question is why can’t it be used for endometrial protection also for 8 years? Awaiting research seems to be the answer whether the smaller amount of levonorgesterol released after 5 years is sufficient. Obviously, the drop in release is not going to be stepped but rather gradual.
From the new PI
“The in vivo levonorgestrel release rate 24 days after insertion is approximately 21 μg/day, decreasing continuously to approximately 19 μg/day after 1 year, to 11 μg/day after 5 years and to 7 μg/day after 8 years of use.”
Mark Raines 